Research at Wells Medicine
Learn about ketamine research conducted at Wells Medicine
Eligibility
- Ages 18-75
- Receiving IV ketamine with Wells Medicine for depressive symptoms, currently receiving no more than 1 treatment per week
- History of at least 1 acute course of ketamine treatment in the past year
- Current diagnosis of MDD
- Presence of suicidal ideation in last month
- Presence of suicidal ideation with intent in last year
Reasons for Consideration
- Compensation up to $200
- Participation (excluding ketamine infusion appointments) is remote and can be done from everywhere
- Free evidence-based treatment from trained clinical psychologists
- Contribution to a pilot study exploring the feasibility and effects of concurrent psychotherapy during IV ketamine maintenance
Exclusions
- Active or past psychotic symptoms
- Severe alcohol use disorder (AUD)
- Current drug use disorder (DUD)
- Past or current manic episode; diagnosis of bipolar disorder
- A personality disorder that may interfere with ability to engage in research trial
- Prior IPT treatment failure
- Engagement in concurrent psychotherapy or therapy that has been discontinued in the past 3 months
- Pregnancy or unwillingness to use contraceptive methods
- Safety risk warranting inpatient hospitalization per treating ketamine clinician and PI judgment
Eligibility
- Ages 18-80
- Receiving IV ketamine with Wells Medicine for depressive symptoms
- Patient is pursuing an initial series of ketamine infusions. Those new to ketamine or returning after a break are eligible
- Completion of digital onboarding prior to first infusion
Reasons for Consideration
- Compensation up to $650-$750
- Participation (excluding ketamine infusion appointments) is remote and can be done from anywhere
- Enhanced clinical monitoring of your symptoms through the study assessments
- Chance of getting free access to a portable digital treatment that may extend the duration of your depression relief and help you get the most of your ketamine treatments
- Contribution to knowledge of how to help people like yourself
Exclusions
- Psychosis
- Severe substance abuse
Eligibility – MDD (Major Depressive Disorder)
- Ages 21-55
- Receiving IV ketamine with Wells Medicine for a current or past diagnosis of depression
- Patient is receiving maintenance infusions or pursuing a series of ketamine infusions. Those new to ketamine or returning after a break are eligible
- Completion of in-person onboarding prior to first infusion
Eligibility – TRD (Treatment-Resistant Depression)
- Ages 21-55
- Patient has tried at least one antidepressant in the past
- Receiving IV ketamine with Wells Medicine for a current or past diagnosis of depression
- Patient is pursuing a series of ketamine infusions. Those new to ketamine or returning after a break are eligible
- Completion of in-person onboarding prior to first infusion
Reasons for Consideration
- Compensation up to $250 (MDD patients) or $450 (TRD patients)
- Uber ride to first infusion (MDD patients) or first and fourth infusions (TRD patients)
- Evaluation and consultation with a psychiatrist
- Bloodwork
- Contribution to knowledge of how ketamine helps people like yourself
Exclusions
- Psychosis
- Bipolar disorder
- Schizophrenia
- Pregnancy



